Applications of Tomographic Imaging in Nuclear Medicine
نویسنده
چکیده
..................................................................................................................................... 2 Glossary ..................................................................................................................................... 4 List of papers ............................................................................................................................. 5 Introduction & history............................................................................................................... 7 Photon detection ........................................................................................................................ 7 Gamma Camera......................................................................................................................... 8 Planar Imaging.................................................................................................................................. 8 3D imaging with a gamma camera ................................................................................................ 10 Single Photon Emission Computed Tomography, SPECT.......................................................................... 10 Ectomography ................................................................................................................................. 11 Positron Emission Tomography, PET.................................................................................... 12 Image reconstruction in nuclear medicine............................................................................. 14 Filtered Backprojection.................................................................................................................. 14 Iterative methods ............................................................................................................................ 14 ML-EM iterative method............................................................................................................................. 15 Results devices and methods in nuclear imaging ................................................................ 17 Paper I. A Gamma camera demonstrator for medical imaging and design of a SPECT phantom ........................................................................................................................................... 17 Papers II and III: The miniPET: a small animal PET camera................................................... 20 The miniPET hardware................................................................................................................................ 20 Event processing.......................................................................................................................................... 20 Image reconstruction ................................................................................................................................... 22 Test and performance measurements........................................................................................................... 24 Paper IV: Cardiotom, a dedicated gamma camera for myocardial heart studies .................... 26 Segmented collimators ................................................................................................................................ 26 The new hardware ....................................................................................................................................... 27 The data acquisition and reconstruction software........................................................................................ 28 Description of my own contribution to the papers included in this Licenciate Thesis......... 30 References ............................................................................................................................ 31 Acknowledgment ..................................................................................................................... 33
منابع مشابه
Production, quality control and imaging of 64Cu-ATSM in healthy rabbits for clinical applications
Introduction: [64Cu]diacetyl-bis(N4-methylthiosemicarbazone) ([64Cu]ATSM) is a well-established hypoxia imaging tracer with reproducible production and significant specifity. In this work the high yield production and quality control as well as imaging studies in healthy rabbits is reported. Methods: Copper-64 produced ...
متن کاملClinical utility of indigenously formulated single-vial lyophilized HYNIC-TOC kit in evaluating Gastro-entero Pancreatic neuro endocrine tumours
Objective(s): The objective of this study was to evaluate the performance and utility of 99mTc HYNIC-TOC planar scintigraphy and SPECT/CT in the diagnosis, staging and management of gastroenteropancreatic neuroendocrine tumors (GPNETs). Methods: 22 patients (median age, 46 years) with histologically proven gastroentero-pancreatic NETs underwent 99mTc HYNIC-TOC whole body scintigraphy and regi...
متن کاملRadiolabeling and Biodistribution of new dual modality nanoparticle probe in Nuclear Medicine
Introduction: Dual-modality contrast agents, such as radiolabeled nanoparticles, are promising candidates for a number of diagnostic applications, namely SPECT imaging with MR imaging. So the aim of study was evaluating potential of Chitosan-Coated Magnetic Nanoparticles(SPION) labeled with 99mTc as new Dual-modality probes for liver Imaging. Materials and Methods:</st...
متن کاملPerformance Evaluation of FBP Reconstruction in SPECT Imaging
Introduction: The purpose of this study is to define the optimal parameters for the tomographic reconstruction procedure in a routine single photon emission tomography. The Hoffman brain phantom is modified to evaluate the reconstruction method. The phantom was imaged in a 3 and 2-dimensional conformation and the results were compared. Materials and Methods: The 2D phant...
متن کاملFeasibility of portable gamma camera imaging in intraoperative radioguided parathyroid adenoma identification
Novel surgical applications include radioguided procedures in parathyroidectomy operations. In order to investigate the feasibility of usage of the portable gamma camera in parathyroidectomy operations; intraoperative radioguided parathyroidectomy operation was performed in three hyperparathyroidism patients with inconclusive preoperative parathyroid scintigraphy results. Intraoperative portabl...
متن کاملMyocardial Perfusion SPECT Imaging in Dextrocardia with Situs Inversus: A Case Report
Dextrocardia is a cardiac positional anomaly in which the heart is located in the right hemithorax with its base-to-apex axis directed to the right and caudad. Situs inversus is an autosomal recessive disorder that causes organs in the chest and abdomen to be positioned in a mirror image from their normal position. Dextrocardia may occur in isolation or as part of situs inversus. Similarly, sit...
متن کامل